One of my core principles is running different plays out of the same 'look' and running the same play out of differing sets. Those principles offer lots of creative challenge, in addition to the usual challenge of 'training up' players.
This is not a play we have, just something to stimulate innovation. We run a series of BOB (baseline out of bounds) plays from the 'STACK-ISO' formation. How would I design something new?
Understand the core principles (spacing, cutting, screening, passing).
Where are the opportunities/targets?
On this play, where do the potential scorers go?
Are there weaknesses, such as poor rebounding (here) or defensive balance?