Can One Set Flow into Diversified Offense?

Can one set of "lines on the page" flow into most offense? I've seen a lack of "early offense" through the years as players congest the middle. 

(Top frames) Spread, Horns

(Bottom frames) 1-3-1, 1-4 Low

Right, two 'guard' front (next best passer out)

4 out, 1 in 

We can run pick-and-roll or dribble handoff out of most of these sets. 

Spread formations are ideal for dribble drive, give-and-go, and back cuts. 

Horns offers a myriad of possibilities;

Horns offers a great set into Flex. 

Carla Berube's Tufts Jumbos ran terrific back cut action out of a minor modification. 

It's easy to run DHO options out of 4 out, 1 in sets. 

It even flows nicely into zone attack. 

Or into a handback screen attack. 

Two critical elements are teaching players "how to play" and their ability to finish. Starting with spacing goes a substantial way to finishing better. Better spacing, teaching more players to drive and dish, and extending shooting ranges are three important dimensions toward higher scoring this season.