Our team has many needs so we'll never discuss this, but the topic is worthy. A few thoughts to ponder...
Players need clarity and direction. It's about choice, not chance. We'll be lucky to have one 'closer', never mind expecting multiple.
Employ principles of mismatches, misdirection, and reversals.
Mismatches. Emphasize off-ball screens to establish mismatches. Screens can go outside in (as shown) or inside out to get small on big speed mismatch.
Misdirection can add value.
The perimeter player screens down to initiate the high ball screen. When the screen-and-roll occurs, 4 rolls up to move the help defender. The point guard gets a lot of options - drive, pass to roller or pick-and-pop, pass to 4 or 2 depending on 'helper' actions.
Reversals. Against zone, players consider actions "behind" the zone.